XARELTO®: Dosing for stroke risk reduction in patients with nonvalvular atrial fibrillation (NVAF)
WITH 24-HOUR STROKE RISK REDUCTION1,2
ONCE-DAILY DOSING* WITH 24-HOUR STROKE RISK REDUCTION1,2
*Taken with evening meal.
No dose adjustment based on weight
Once daily with the evening meal in patients with CrCl >50 mL/min
MODERATE TO SEVERE RENAL IMPAIRMENT DOSE
Once daily with the evening meal in patients with CrCl ≤50 mL/min
Renal Dosing Considerations
- Adjust XARELTO® dose based on renal function
- Periodically assess renal function as clinically indicated (ie, more frequently in situations in which renal function may decline) and adjust therapy accordingly
- Consider dose adjustment or discontinuation of XARELTO® in patients who develop acute renal failure while taking XARELTO®
- See sections 2.1 and 8.6 of the Prescribing Information for additional information
◇For VTE prophylaxis in acutely ill medical patients at risk for thromboembolic complications who are not at high risk of bleeding.
CrCl = creatinine clearance; NVAF = nonvalvular atrial fibrillation; VTE = venous thromboembolism.