XARELTO®: Dosing for stroke risk reduction in nonvalvular atrial fibrillation (NVAF)

ONCE-DAILY DOSING* WITH 24-HOUR STROKE RISK REDUCTION1,2

*Taken with evening meal.

20 mg

Once daily with the evening meal in patients with CrCl >50 mL/min

15 mg

MODERATE TO SEVERE RENAL IMPAIRMENT DOSE


Once daily with the evening meal in patients with CrCl ≤50 mL/min

Renal Dosing Considerations

  • Adjust XARELTO® dose based on renal function
  • Periodically assess renal function as clinically indicated (ie, more frequently in situations in which renal function may decline) and adjust therapy accordingly
  • Consider dose adjustment or discontinuation of XARELTO® in patients who develop acute renal failure while taking XARELTO®
  • See section 8.6 of the Prescribing Information for additional information