XARELTO®: Dosing in deep vein thrombosis (DVT) prophylaxis after hip or knee replacement surgery

DVT PROPHYLAXIS WITH ONCE-DAILY DOSING

10 mg

Once daily for 35 days, 6-10 hours after surgery once hemostasis has been established in patients with a CrCl ≥30 mL/min

10 mg

Once daily for 12 days, 6-10 hours after surgery once hemostasis has been established in patients with a CrCl ≥30 mL/min

Renal Dose Consideration
  • Avoid using XARELTO® in patients with CrCl <30 mL/min

CrCl = creatinine clearance;