XARELTO®: Dosing for coronary artery disease (CAD)
Twice daily with or without food in combination with aspirin (75 mg to 100 mg) once daily
No dose adjustment needed based on CrCl
Renal Dosing Considerations
CAD and/or PAD: For patients with CrCl <15 mL/min, no data are available, and limited data are available for patients with a CrCl of 15 to 30 mL/min. Clinical efficacy and safety studies with XARELTO® did not enroll patients with end-stage renal disease (ESRD) on dialysis.
CAD = coronary artery disease; CV = cardiovascular; MI = myocardial infarction.