*Patients with chronic coronary syndromes (chronic CAD) and in sinus rhythm.

XARELTO® 2.5 mg twice daily with aspirin 100 mg once daily.

Major cardiovascular events were a composite of cardiovascular death, myocardial infarction, or stroke.

CAD = coronary artery disease; CV = cardiovascular; DOAC = direct oral anticoagulant; ESC = European Society of Cardiology; MI = myocardial infarction; PAD = peripheral artery disease.