XARELTO®: Venous thromboembolism (VTE) platform and
condition-specific dosing

XARELTO®: Venous thromboembolism (VTE) platform and condition-specific dosing

XARELTO® treats and helps protect against DVT/PE wherever your patients need it—inpatient and outpatient*1-7

VTE Platform

Treatment and reduction in the risk of recurrence

H C P determination for duration of therapy
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H C P determination for duration of therapy
View Dosing>

VTE prophylaxis

H C P determination for duration of therapy
View Dosing>

H C P determination for duration of therapy
View Dosing>

Condition-specific dosing‡§ǁ¶

DVT/PE
Initial treatment DOSING
DVT/PE
Extended treatment DOSING
DVT Prophylaxis
After hip/knee replacement surgery DOSING
VTE Prophylaxis
Acutely ill medical patients◇ DOSING

◇For VTE prophylaxis in acutely ill medical patients at risk for thromboembolic complications who are not at high risk of bleeding.

*The decision regarding initiation setting should be based on the prescriber’s clinical judgment.

†Administer 6 to 10 hours after surgery once hemostasis has been established.

‡Avoid use in patients with CrCl <15 mL/min.

§Discontinue XARELTO® in patients who develop acute renal failure while on treatment.

ǁCalculate CrCl based on actual weight.

Patients with CrCl <30 mL/min were not studied, but administration of XARELTO® is expected to result in serum concentrations of rivaroxaban similar to those in patients with moderate renal impairment (CrCl 30 mL/min to <50 mL/min).

CrCl = creatinine clearance; DVT = deep vein thrombosis; HCP = healthcare professional; LTC = long-term care; PE = pulmonary embolism; VTE = venous thromboembolism.